it cant be too much vacuum to the motor because for one, the catch can is vented to atmosphere.
if you have a lot of blowby that is as sign of engine condition. a motor cant pull so much vaccum that it pulls oil mist out of the rockers on its own, its blown up and out by the blow by.
an engine with a fair bit of blowby isnt ideal, but with a decent large catch can can be managed.