Got this yesterday, I have an E6750 Core 2 Duo@3ghz, and AMD 6970, gotta say, this thing is buttery smooth on hardcore, I think it even runs better than Crysis 1!!!
SP is pretty lame for the first hour or so but it gets way better
You can really tell that it's an console port though, when you first start it up it asks you to 'adjust the brightness on your TV', plus there are literally no adjustable settings for graphics other than normal, gamer, hardcore etc. You can I've heard adjust these things through screwing around with the console/config files I've heard though.