if you have iridium plugs just be careful when you are gaping the because the iridium is only a few microns (1000th's of a mm) thick and if you scratch it it will come off and ruin you expensive plugs.
IMO there is no point running them as they don't do a better job than the copper plug they just do if for longer' they were designed to be fitted to cars that are hard to change plugs like 300zx's and WRX's so you don't have to change them every 5-10,000 you can stretch that out to 70,000-100,000. Platinum's are the same story.