my gtr did it, my 180sx did it for 2 years, the 180 im drivin now has massive "dose", my rx7 that i had also sounded like a vl turbo tututututututu...
never had a problem.. but i assume that while it may cause damage to the turbo, its probably minimal.. unless ur running high boost.. might snap the wheel off the shaft lol
ive heard of that happening b4