Funny you should mention the APS kit.....my brother just had the twin turbo kit fitted to his 6 litre Commodore. It pumped out just over 500 rwhp at around 7.5 psi. Admittedly the intercooler is not working hard in terms of boost levels but 500 rwhp gives you an idea of it's flow capabilities. Full boost at 3250 rpm with a pair of 500 hp turbo's with .86ar turbine and thats with no boost controller.....just running 7psi wastegate springs.
The hot pipes enter at an angle from each side into the bottom of the intercooler and exits to a big outlet to the passenger side and up and around to the t/b.
ARE have some info on there site re intercoolers sizing. From memory the 'window' into the cooler core must be sized according to flow of the turbo ....too small and it will cause a restriction whilst the length of the cooler core is sized according to how hard you want to boost the turbo i.e. the higher the boost the longer the core. However, the longer the core the greater the pressure drop. Big efficient turbos can probably use the shorter vertical cores with a large window area to accommodate the flow requirements of the turbo.