New graphics card appeared to be DOA... was actually stopping my computer from booting up at all, old gfx card still working fine.
Updated to the "Latest" BIOS version according to the MSI Live Updater, still dead with the card plugged in...
Discovered that there were Beta BIOS's for my Motherboard as well, 18 months newer than the "Latest" BIOS that the MSI Site supplied me with.
Flashed one of them on, Bob's your slightly creepy uncle, up and running like a champ. Tonight, I shall play watch dogs at High Settings instead of Pov Spec.
Can't wait for this day to be over.