I feel there will be a lot less stress on the rods if you can run e85, even though the torque is increased due to the slower burning properties. More boost, less timing could help too but it's just my opinion, and everyone will tell you a different story. One thing is for sure, the life of the engine will be severely reduced no matter how it's tuned. Make sure you find a good tuner and go with what he suggests.
The benefit of the emanage is you can tune off the map sensor once the afm is maxed, much better than guessing the airflow beyond that point.