the real problem lies within the flow of the injectors not the impedence, since rb25 squirters are 370cc's the pfc expects 370's, not the 270's as standard on a rb20.
if you are planning to upgrade injectors (which on a rb20 should be done anyways) then it doesnt matter, but for those who arnt then its not such a hot idea.
again it will run with the 270's but very poorly due to the pfc expecting larger injectors.
since both the rb25 and rb20 use high imp injectors you may need to use a resistor pack depending on what injectors you end up using, ive got some denso 720's which are low imp so ive a resistor pack to suit.